Pathology Images

The following images are provided to support the text from the following article in Vol. 18, No. 1 of the ACLAD Newsletter:

Diagnostic Exercise: Interstitial pneumonia in viral and mycoplasmal antibody-free Sprague Dawley Rats

Patricia L. Farrar, DVM, MS, Dipl. ACLAM

Department of Comparative Medicine, St. Louis University Health Sciences Center

Marie LaRegina, DVM, MS, Dipl. ACLAM

Division of Comparative Medicine, Washington University School of Medicine

Figure 1. Lung, rat. H&E stain, 100X. Perivascular accumulation of mononuclear cells, adjacent to foci of mild alveolitis.

Figure 2. Lung, rat. H&E stain, 400X. Mild alveolitis, characterized by foamy macrophage and lymphocyte accumulations in the alveolar lumen, and alveolar septal thickening with inflammatory cells.

Figure 3. Lung, rat. H&E stain, 40X. Low power view of a subpleural foci of nonsuppurative interstitial pneumonia.

Figure 4. Lung, rat. H&E stain, 100X. Higher power view, showing extensive nonsuppurative interstitial pneumonia, with diffuse alveolar septal thickening and inflammatory cells in nearly all alveolar spaces.

Figure 5. Lung, rat. Toluidine blue stain, epoxy embedding, 200X. Thin section showing perivascular mononuclear cell aggregate adjacent to mild foci of granulomatous alveolitis. Note several alveoli contain increased numbers of alveolar type II cells (type II hyperplasia).

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Pathology Images

The following images are provided to support the text from the following article in Vol. 18, No. 1 of the ACLAD Newsletter:

Diagnostic Exercise: Interstitial pneumonia in viral and mycoplasmal antibody-free Sprague Dawley Rats

Figure 1. Lung, rat. H&E stain, 100X. Perivascular accumulation of mononuclear cells, adjacent to foci of mild alveolitis.

Figure 2. Lung, rat. H&E stain, 400X. Mild alveolitis, characterized by foamy macrophage and lymphocyte accumulations in the alveolar lumen, and alveolar septal thickening with inflammatory cells.

Figure 3. Lung, rat. H&E stain, 40X. Low power view of a subpleural foci of nonsuppurative interstitial pneumonia.

Figure 4. Lung, rat. H&E stain, 100X. Higher power view, showing extensive nonsuppurative interstitial pneumonia, with diffuse alveolar septal thickening and inflammatory cells in nearly all alveolar spaces.

Figure 5. Lung, rat. Toluidine blue stain, epoxy embedding, 200X. Thin section showing perivascular mononuclear cell aggregate adjacent to mild foci of granulomatous alveolitis. Note several alveoli contain increased numbers of alveolar type II cells (type II hyperplasia).

Last modified 6/21/00 bjw